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Similac for Spit-Up in Healthy Infants with Iron and OptiGRO

By Similac


  • Clinically shown to reduce spit-up
  • Prebiotics promote digestive health
  • Available in multiple size containers
  • Ready-to-drink option available
  • Reduced lactose formula
  • Contains DHA for brain and eye development
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50959 Similac for Spit-Up in Healthy Infants with Iron and OptiGRO

12 oz. Can - Each


50959 Similac for Spit-Up in Healthy Infants with Iron and OptiGRO

12 oz. Can - Case of 6


53729 Similac for Spit-Up in Healthy Infants with Iron and OptiGRO

SimplePac 1.41 lb - Each



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Similac Spit-Up in Healthy Infants Formula with Iron and OptiGRO is a specialized milk-based infant formula with added rice starch to reduce frequent spit-up since it's easier to digest. Similac Spit-Up Formula has been clinically shown to reduce frequent spit-up in healthy babies by 54 percent, among healthy 2-month-old infants, compared to standard formula. In addition, the formula contains prebiotics to promote digestive health. This formula is iron-fortified for baby's growth and brain development. Abbott Nutrition developed an exclusive blend of important ingredients found in breast milk called OptiGRO. This blend includes DHA for brain and eye development, lutein to support eye health and vitamin E to support developing cells. In addition, it contains calcium for strong bones and carotenoids that are naturally found in breast milk found to act as antioxidants to fight off disease.

Infants with other dietary needs will find Similac for Spit-Up Infant Formula to be Kosher, Halal and gluten-free. Formula can be purchased in 12.03 oz and 1.41 lb Can of powder formula and 1-Quart Ready-to-Feed Bottle. Powdered infant formulas are not sterile and therefore should not be fed to premature infants or infants with compromised immune systems. The Ready-to-Feed bottle may be the best option, consult with your baby's physician.

Features, Benefits, Specifications, Ingredients, Precautions, Storage, Handling, Preparation and Nutrition Information

Features and Benefits:

  • Reduced Lactose Formula
  • Easier to Digest
  • Prebiotics for Digestive Health
  • Reduces Spit-up
  • Contains Ingredients Found in Breast Milk
  • Promotes Brain and Eye Development
  • Promotes Strong Bones
  • Kosher
  • Halal
  • Gluten-free


  • Manufacturer: Abbott Nutrition
  • Item Numbers: 50959, 53729, 56728
  • Sizes: 12.3 oz Can (50959). 1.41 lb SimplePac (53729), 1-Quart Ready-to-Feed Bottle (56728)
  • HCPCS Code: B4158


Powder Unflavored: Corn Syrup, Modified Rice Starch, Milk Protein Isolate, High Oleic Safflower Oil, Sugar, Soy Oil, Coconut Oil, Galactooligosaccharides. Less than 2% of: C. Cohnii Oil, M. Alpina Oil, Beta-Carotene, Lutein, Lycopene, Calcium Phosphate, Potassium Citrate, Potassium Chloride, Potassium Phosphate, Calcium Carbonate, Magnesium Chloride, Ascorbic Acid, Choline Chloride, L-Cystine Dihydrochloride, Ascorbyl Palmitate, Salt, Ferrous Sulfate, Choline Bitartrate, Taurine, m-Inositol, Mixed Tocopherols, Zinc Sulfate, L-Carnitine, Niacinamide, d-Alpha-Tocopheryl Acetate, Calcium Pantothenate, Vitamin A Palmitate, Cupric Sulfate, Thiamine Chloride Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Potassium Iodide, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Cyanocobalamin, Potassium Hydroxide, and Nucleotides (Adenosine 5’-Monophosphate, Cytidine 5’-Monophosphate, Disodium Guanosine 5’- Monophosphate, Disodium Uridine 5’-Monophosphate). Allergens: Contains milk ingredients.


  • Warm ready-to-feed formula by pouring needed amount into a bottle and then place in warm water. Do not microwave which can boil and cause serious harm to baby.
  • Similac Spit-Up is not intended for infants or children with galactosemia allergy.
  • Powdered infant formula is not sterile. Ready-to-Feed formula is best for premature infants or infants with a compromised immune system. Consult with pediatrician.

Storage and Handling:

Powder (12.3 oz and SimplePac 1.41 lb Can)

  • Once powder is mixed with water, store unused bottles in refrigerator and feed to baby within 24 hours.
  • Store unopened or opened container at room temperature.
  • Do not expose formula to extreme temperatures.
  • To maintain freshness and nutritional value, use opened container within one month.
  • Do not reuse Similac container for other purposes.

Ready-to-Feed (1 Quart) Bottle

  • Store unopened containers at room temperature.
  • Do not expose formula to extreme temperatures.
  • Store Ready-to-Feed container in refrigerator.
  • Store prepared bottles in refrigerator and feed to baby within 48 hours.
  • Once bottle has been opened, the formula in container must be fed to the baby within three days.
  • Do not reuse Similac container.

Similac For Spit-Up Preparation Instructions

Powder Nutrition Information

Volume155.5 mL (5.3 fl oz)1000 mL (1.1 Qt)
Protein2.14 grams13.76 grams
Fats5.40 grams34.73 grams
Carbohydrates11 grams70.74 grams
Water140 grams902 grams
Linoleic Acid1000 mg6431 mg
Vitamin A300 IU1929 IU
Vitamin D60 IU1386 IU
Vitamin E1.5 IU9.6 IU
Vitamin K8 mcg51.4 mcg
Thiamin (Vitamin B1)100 mcg643 mcg
Riboflavin (Vitamin B2)160 mcg1029 mcg
Vitamin B663 mcg405 mcg
Vitamin B120.26 mcg1.67 mcg
Niacin1100 mcg7074 mcg
Folic Acid16 mcg102.9 mcg
Biotin4.6 mcg29.6 mcg
Pantothenic Acid470 mcg3023 mcg
Vitamin C9 mg57.9 mg
Choline24 mg154.3 mg
Inositol4.5 mg28.9 mg
Calcium88 mg566 mg
Calcium4.4 mEq28.3 mEq
Phosphorus59 mg379 mg
Magnesium6 mg38.6 mg
Copper95 mcg611 mg
Iron1.9 mg12.22 mg
Zinc0.79 mg5.08 mg
Manganese5 mcg38.6 mcg
Iodine9 mcg58 mcg
Selenium2 mcg13 mcg
Sodium32 mg206 mg
Sodium1.4 mEq9 mEq
Potassium110 mg707 mg
Potassium2.8 mEq18 mEq
Chloride68 mg437 mg
Chloride1.9 mEq12.2 mEq
Additional Information

Additional Information

Manufacturer Abbott Nutrition
Brand Similac

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