High-Level OPA Disinfection for Reusable Medical Devices
Metrex MetriCide OPA Plus is a high-level disinfectant solution formulated with 0.55% ortho-phthalaldehyde (OPA) for use on heat-sensitive, semi-critical medical devices. The MetriCide OPA Plus solution is ready to use and requires no activation, providing a reliable alternative to glutaraldehyde-based products.
It delivers efficient disinfection with a contact time of 12 minutes at 20°C for manual use, or 5 minutes at 25°C in automated endoscope reprocessors (AERs). The solution is effective for up to 30 days manually or 14 days in an AER, making it ideal for hospitals, outpatient clinics, and surgical centers that demand consistent, compliant instrument reprocessing.
Trusted by healthcare professionals, Metrex MetriCide OPA Plus solution supports rapid turnaround, material compatibility, and odor reduction while maintaining high-level disinfection standards across a wide range of reusable medical tools.
Features and Benefits
- Ready-to-use OPA solution; no activation required
- 5-minute disinfection in AERs at 25°C
- Manual disinfection in 12 minutes at 20°C
- Reusable for up to 30 days (manual) or 14 days (AER)
- OPA-based and glutaraldehyde-free to reduce irritation
- Safe for use on endoscopes, probes, and heat-sensitive devices
- Low odor and surfactant-free to maintain lens clarity
- Disinfects a wide range of bacteria, viruses, fungi, and mycobacteria
- Delivers up to 33% faster disinfection than other OPA products
Efficacy
- Manual disinfection:
- 12 minutes at 20°C (68°F)
- Reusable for up to 30 days with test strip validation
- Automated disinfection (AER):
- 5 minutes at 25°C (77°F)
- Reusable for up to 14 days with test strip validation


Product Specifications
- Product Name: MetriCide OPA Plus
- Brand: MetriCide
- Manufacturer: Metrex Research
- Item Number: 10-6000
- Application: High-level disinfectant
- Active Ingredient: 0.55% ortho-phthalaldehyde (OPA)
- Use Life: Up to 30 days (manual), 14 days (AER)
- Contact Time: 12 minutes at 20°C (manual); 5 minutes at 25°C (AER)
- Format: Ready-to-use liquid
- Volume: 1 gallon
- Container Type: Jug
- pH Range: 7.0 to 7.8
- Scent: Mild
- Color: Bluish green
- Form: Liquid
- Latex-Free: Not made with natural rubber latex
- Compatibility: Endoscopes, probes, and heat-sensitive devices
- Country of Origin: China
Frequently Asked Questions (FAQs)
Will MetriCide OPA Plus solution irritate the skin?
MetriCide OPA Plus may cause moderate skin irritation. Always wear protective gloves and avoid contact with eyes or skin.
Can OPA stain clothing?
Yes, it may stain fabrics. Contaminated clothing should be removed and laundered before reuse.
Does this product contain glutaraldehyde?
No. MetriCide OPA Plus is glutaraldehyde-free and uses OPA as its active disinfecting agent.
Microorganisms and Pathogens
Viruses: Poliovirus type 1, Rhinovirus type 42, Hepatitis A (AER), Influenza A, HIV-1, Herpes simplex type 1, Duck hepatitis B, Avian influenza A
Bacteria: Staphylococcus aureus, Salmonella choleraesuis, Pseudomonas aeruginosa, Mycobacterium tuberculosis var: bovis
Fungi: Trichophyton mentagrophytes
Manuals and Documents
Safety Data Sheet provides sporicidal, tuberculocidal, bactericidal, and fungicidal test results with other toxicity study findings.
Test Result Technical Bulletin provides sporicidal, tuberculocidal, bactericidal, and fungicidal test results with other toxicity study findings.
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