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CryoDerm Pain Relieving Cold Therapy - Full Product Line | Gel, Spray, Gallon, Packets

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CRO100 CryoDerm Pain Relieving Cold Therapy

4 oz. Spray - Each


CRO101 CryoDerm Pain Relieving Cold Therapy

4 oz. Gel - Each


CRO102 CryoDerm Pain Relieving Cold Therapy

3 oz. Roll on - Each


CRO103 CryoDerm Pain Relieving Cold Therapy

16 oz. Spray - Each


CRO104 CryoDerm Pain Relieving Cold Therapy

16 oz. Clinic Gel Pump Bottle - Each


CRO105 CryoDerm Pain Relieving Cold Therapy

32 oz. Clinic Spray Bottle - Each


CRO106 CryoDerm Pain Relieving Cold Therapy

3 Gram Packet - Each


CRO109 CryoDerm Pain Relieving Cold Therapy

Gallon Bottle - Each


CRO110 CryoDerm Pain Relieving Cold Therapy

32 oz. Pump - Each



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Product Overview

CryoDerm is a soothing Cold Therapy topical analgesic gel for pain relief. Cryoderm gel deeply penetrates the muscle while giving an instant cooling sensation for targeted cryotherapy cold therapy. For this reason, Cryoderm Cold Therapy Pain Relief is used in sports medicine, chiropractic, physical therapy, rehabilitation, and massage therapy, but it's also an ideal solution for active individuals who put their bodies to the test. It comes in a variety of sizes and applicator options, such as spray, gel, roll-on gel, and CryoDerm 1-gallon bottles.

CryoDerm Size Options

Cryoderm Uses

  • Muscle Strains
  • Sore Muscles
  • Joint Pain
  • Backache
  • Arthritis
  • Swelling in the Joints
  • Sprained Ligaments
  • Knee Pain
  • Bruises
  • Deep Tissue Massage, Myofascial Release, and Trigger Point Therapy

How Cold Therapy Works

Pain Cycle

The CryoDerm Pain-Relieving Cold Therapy offers clinical-strength pain relief that effectively reduces pain and muscle spasms. The all-natural formula incorporates essential oils and extracts with a concentration of menthol to create a long-lasting cooling effect to treat pain and increase blood flow to remove inflammation.

The Power of Menthol USP

Menthol USP is an organic compound that's extracted from the peppermint plant. The compound produces a cooling sensation that significantly reduces pain intensity. The cooling effect is soothing, but it's also triggering the skin's cold receptor neurons to mitigate pain reception. Its natural cooling properties have been clinically proven to offer pain relief and reduce inflammation.1

Often the pain is related to swelling and menthol also has an anti-inflammatory role. Together with the active ingredients Arnica and Boswellia, blood flow is increased to reduce inflammation to further reduce pain and discomfort. CryoDerm Pain Relief products have a higher menthol concentration -- 10% -- than similar products like Biofreeze, which uses 5% menthol.

CryoDerm Ingredients

Other Active Ingredients

CryoDerm Ingredients

  • Peppermint Oil: Peppermint delivers a burning-cold sensation. It also has anesthetic properties and promotes blood flow.
  • Arnica: This yellow herb is diluted to reduce pain and reduce inflammation to be helpful with muscle soreness, joint irritation, and swelling.
  • Eucalyptus: Its leaves contain antioxidants that fight bacteria and have pain-relieving properties.
  • Ilex: Is a leaf from the Holly tree and is used to loosen the joint and reduce swelling.

How to Apply

  • There are many applicator options. The gel can be dispensed from a pump bottle, packet, spray, and roll-on and massaged into the skin. CryoDerm Roll-On applicator easily glides against the skin to spread the gel on the affected area. The CryoDerm spray evenly distributes the formula and can be left alone to dry or it can be massaged into the skin.
  • Repeat as necessary, up to four times a day.

Features and Benefits

  • Offers Fast, Penetrating Pain Relief
  • Applies Colorless With No Mess
  • Reduces Inflammation
  • Greaseless, Non-Staining
  • Higher Content of Soothing Menthol
  • Uses Natural Menthol, Essential Oils and Extracts
  • Powerful Cold Therapy
  • CryoDerm 1-Gallon Bottle Ideal for Clinics

Product Specifications

  • Manufacturer: CryoDerm
  • Product Numbers: CRO100, CRO101, CRO102, CRO103, CRO104, CRO105, CRO106, CRO109, CRO110
  • Made in the U.S.
  • Variations: Packet, Spray, Roll-On, Gel, or Pump Bottle
  • HCPCS: A9270
  • Menthol Strength: 10%


Menthol USP, Arnica Montana Flower, Boswellia, Eucalyptus Oil, Glycerin, Ilex Paraguariensis Leaf, Dimethyl Sulfone, Peppermint Oil, Purified Water, Alcohol, Trolamine, Alklyl Methacrylate Ester


  • Consult with a health care professional before use if pregnant or breastfeeding.
  • Keep away from excessive heat or an open flame.
  • If redness or irritation is present after use, stop, and wash off.
  • External use only.

Complementary Products

Manuals and Documents



Product Videos


How CryDerm Works Video (2:56 minutes)



Additional Information

Additional Information

Manufacturer Cryoderm

Shipping & Returns

Shipping Information

Leaves Warehouse: 1-2 business days - More details
Economy Shipping: Guaranteed 7-10 business days

Returns Information
Refer to our returns policy for more information.


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