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SilverSeal Hydrogel dressings are cross-linked polymer based gels that may be made into sheets. Unlike antibiotics, silver works through a multimodal mechanism of action whereby pathogens from exudating wounds are safely eradicated. Silver technology has increasingly become a mainstay in hospitals in the past 3-5 years to thwart the incidence of hospital acquired infections. Silver based wound dressings are becoming increasingly prevalent in wound care due to the recent increase of antibiotic-resistant bacteria such as methicillin-resistant Staphylococcus aureus, known as MRSA. Silver, when moist, emits ions. Silver ions (Ag+) are bioactive and in sufficient concentration readily kill bacteria in both external wounds and in living tissue. Unlike competing products, which are largely dry in nature, Alliqua's dressing is approximately 95% water based; and hence, does not have the issues of requiring pre-wetting or absorption of transdermal water loss or wound exudate to become bioactive. Alliqua's SilverSeal Hydrogel sheets can hold themselves in place; however, they are non-adherent (they do not bond to the wound, skin or hair) and thus can be removed without causing additional trauma to the wound bed. While many hydrogels are not highly absorptive, Alliqua's hydrogels can absorb 2.5X their weight in exudate. Borderless hydrogel dressings may require secondary dressings.
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