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Liquid Oxygen

Liquid Oxygen (LOX) is used as therapy for respiratory patients. Medical oxygen in liquid form offers several advantages over the other two oxygen therapy modes. These two modes consist of compressed oxygen or concentrated oxygen. Compressed oxygen is usually dispensed through oxygen cylinders or tanks while concentrated oxygen is offered by electrically powered concentrator machines. Liquid oxygen is stored and dispensed in the home by an oxygen reservoir. This reservoir also refills the portable units that are carried by the oxygen patient while away from the home. Liquid oxygen therapy is lightweight, offers longer duration, provides 100% oxygen, requires no batteries or electrical power, recharges in less than two minutes and offers both continuous flow and pulse flow.

Chart Industries is the premier manufacturer in the United States for liquid oxygen devices. Their most popular liquid oxygen brands are the HELiOS and the Companion. Vitality Medical carries both of these LOX brands.

LOX has been studied by medical professionals around the world and compared with compressed oxygen and concentrated oxygen in numerous studies. Below is a list of resources highlighting some of these studies.

Liquid Oxygen Resources

  1. Tarpy, Stephen P., and Bartolome R. Celli. "Long-term oxygen therapy." New England Journal of Medicine 333.11 (1995): 710-714.
  2. Nasilowski, Jacek, et al. "Comparing supplementary oxygen benefits from a portable oxygen concentrator and a liquid oxygen portable device during a walk test in COPD patients on long-term oxygen therapy." Respiratory medicine 102.7 (2008): 1021-1025.
  3. Krop, Harry D., A. Jay Block, and Edwin Cohen. "Neuropsychologic effects of continuous oxygen therapy in chronic obstructive pulmonary disease."CHEST Journal 64.3 (1973): 317-322.
  4. Pepin, Jean-Louis, et al. "Long-term oxygen therapy at home: compliance with medical prescription and effective use of therapy." CHEST Journal109.5 (1996): 1144-1150.
  5. Eaton, T., et al. "Long-term oxygen therapy improves health-related quality of life." Respiratory medicine 98.4 (2004): 285-293.
  6. Vergeret, J., C. Brambilla, and L. Mounier. "Portable oxygen therapy: use and benefit in hypoxaemic COPD patients on long-term oxygen therapy."European Respiratory Journal 2.1 (1989): 20-25.
  7. Petty, Thomas L., and Walter J. O'Donohue Jr. "Further recommendations for prescribing, reimbursement, technology development, and research in long-term oxygen therapy. Summary of the Fourth Oxygen Consensus Conference, Washington, DC, October 15-16, 1993." American journal of respiratory and critical care medicine 150.3 (1994): 875-877.
  8. McDonald, C., A. Crockett, and I. Young. "Adult domiciliary oxygen therapy. Position statement of the Thoracic Society of Australia and New Zealand."Medical Journal of Australia 182.12 (2005): 621-626.
  9. Katsenos, Stamatis, et al. "Long-term oxygen therapy in chronic obstructive pulmonary disease: the use of concentrators and liquid oxygen systems in north-western Greece." Respiration 73.6 (2006): 777-782.
  10. Howard, P., and R. De Haller. "Domiciliary oxygen--by liquid or concentrator? Working Group on Oxygen Therapy of IUATLD." European Respiratory Journal 4.10 (1991): 1284-1287.
  11. Lock, S. H., et al. "Comparison of liquid and gaseous oxygen for domiciliary portable use." Thorax 47.2 (1992): 98-100.
  12. Ringbaek, T., P. Lange, and K. Viskum. "Compliance with LTOT and consumption of mobile oxygen." Respiratory medicine 93.5 (1999): 333-337.

Reproduced below is a comparison chart, displaying the average characteristics for LOX vs. continuous/pulse flow portable oxygen concentrators. This chart is from a review by Burt Cancaster entitled "Liquid Oxygen Therapy" that details medical liquid oxygen and compares LOX with oxygen concentrators.

Comparing Liquid Oxygen to Portable Oxygen Concentrators


Additional LOX Resources

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Liquid Oxygen Comments